Amlodipine Besylate Tablets
Amlodipine tablets are a calcium ion influx inhibitor of the dihydropyridine group (slow channel blocker or calcium ion antagonist) and inhibits the transmembrane influx of calcium ions into cardiac and vascular smooth muscle.
The mechanisms of the antihypertensive action of Amlodipine tablets are due to a direct relaxant effect on vascular smooth muscle. The precise mechanism by which Amlodipine tablets relieves angina has not been fully determined but Amlodipine tablets reduces total ischaemic burden by the following two actions.
1) Amlodipine tablets dilate peripheral arterioles and thus, reduce the total peripheral resistance (afterload) against which the heart works. Since the heart rate remains stable, this unloading of the heart reduces myocardial energy consumption and oxygen requirements.
2) The mechanism of action of Amlodipine tablets also probably involves dilatation of the main coronary arteries and coronary arterioles, both in normal and ischaemic regions. This dilatation increases myocardial oxygen delivery in patients with coronary artery spasm.
This product is available in the following dosages:
- Amlodipine besylate 5 mg Tablets
- Amlodipine besylate 10 mg Tablets
Amlodipine Besylate Tablets are available in the following packaging:
- 10 Tablets/blister, 3 blisters/box;
- foil packs or according to the customer's specifications.
Selective Calcium channel blocker
Amlodipine Besylate